Vaccine rumours do rounds

BY SARAH MOYES
Last updated 05:00 27/11/2009

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Myths and legends about the effectiveness of the new cervical cancer vaccine are circulating around Auckland schools.

Gardasil helps protect women against human papillomavirus (HPV) which causes 70 percent of cervical cancer cases and 90 percent of genital warts.

The three dose vaccine is for women aged nine to 26, with girls who were in years 8, 12 and 13 this year receiving it for free through school programmes.

But experts say it is this very group of Auckland school girls who are spreading misconceptions, resulting in many choosing not to get the vaccine.

The Auckland University Immunisation Advisory Centre is conducting a study on the factors that contribute to minor injection site reactions.

Helen Petousis-Harris, director of research and senior lecturer in vaccinology at the centre, is working on the study for her thesis.

She says while trying to recruit girls, many myths and rumours have surfaced which seem to have had an effect on the uptake of the vaccine.

Some common misconceptions are that the vaccine is only effective if the girl has never been sexually active, they are too young to have it and it will make them infertile.

Mrs Petousis-Harris says girls also think the vaccine is being tested on them and they are "guinea pigs".

Although Health Ministry statistics show Auckland's uptake of the vaccine until July was similar to the rest of the country, Mrs Petousis-Harris says she is finding it difficult to enrol young women for the study.

A ministry spokeswoman says the Auckland District Health Board's rate was 56 percent, which is higher than the national rate of 52 percent. She says it is happy with the uptake so far, which has been slowly and steadily climbing.

"We recognise that this is a new immunisation for New Zealand and understand some parents might be taking a wait and see approach before deciding whether or not to choose HPV immunisation for their daughters," the spokeswoman says.

Mrs Petousis-Harris says hearing that myths and rumours about vaccines are circulating is always disappointing.

"Often people become worried that they may be true and choose not to vaccinate.

"It's really important that decisions around vaccination are based on fact not fiction."

The ministry says Gardasil has been extensively tested for safety and effectiveness.

"To date, more than 14 million people have chosen to have the HPV immunisation worldwide."

The ministry says the vaccination works best on girls and young women who haven't yet been exposed to the virus, meaning before they are sexually active.

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But Gardasil is also recommended for young women who are already sexually active.

"This is because it is unlikely they will have been exposed to all the types of HPV the vaccine protects against," the ministry says.

It also wants to assure girls and young women that the vaccine will not make them infertile.

"The studies undertaken for Gardasil show the vaccine has no effect on fertility, the baby's wellbeing or pregnancy outcome."

Mrs Petousis-Harris is still looking for volunteers to take part in her study on Gardasil and minor injection site reactions.

For more information call 923-2078 or text 021-640-425.

- © Fairfax NZ News

2 comments
Post a comment
Tracey P   #2   01:02 pm Nov 30 2009

Elizabeth T is interpreting "GARDASIL has not been evaluated for the potential to cause carcinogenicity or genotoxicity." As meaning (That means there have been no studies to see if Gardasil can cause cancer, or if it can change genetic material (the changes of which can pass on to later offspring who never received the vaccine).

This is a classic error in logic. Firstly, the very large clinical trials evaluated each participant for adverse events including malignancies for 3 years. Secondly, the contents of the vaccine all have well established safety profiles and are commonly used in a range of foods and medicines. Thirdly, there is no biological mechanism by why the vaccine would be likely to cause cancer.

The second statement is really a bit silly because during the trial 2516 participants became pregnant (against instruction from the study investigators). There was no difference in pregnancy rate or fetal outcome between the vaccine group and the placebo group. It is highly unethical to conduct drug trials on pregnant women which is why it is not done.

Elizabeth T.   #1   09:21 am Nov 28 2009

The ministry says, "The studies undertaken for Gardasil show the vaccine has no effect on fertility, the baby's wellbeing or pregnancy outcome."

I find that interesting, since the following is what the vaccine manufacturer's package insert says:

http://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM111263.pdf

"GARDASIL has not been evaluated for the potential to cause carcinogenicity or genotoxicity." (page 14) (That means there have been no studies to see if Gardasil can cause cancer, or if it can change genetic material (the changes of which can pass on to later offspring who never received the vaccine).

It is also stated in the package insert that Gardasil's effects on fertility and pregnancy outcome have only been studied on rats. There have been no such studies on humans.

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