Jennifer Lawrence and Bradley Cooper: 16 Years
Silver Linings Playbook stars Lawrence, 23, and Cooper, 39, have heaps of chemistry, which makes you forget about their age difference on screen. They'll also pair up again in Serena as husband and wife.
Margot Robbie and Leonardo DiCaprio: 16 years
The Wolf of Wall Street likes 'em young. DiCaprio is 39 years old in real life, while his onscreen wife is just 23.
Jennifer Lawrence and Christian Bale: 17 Years
Cooper isn't Lawrence's oldest love interest, though: 40-year-old Bale played her husband in American Hustle.
Rooney Mara and Daniel Craig: 17 Years
He's extremely sexy, but the age gap between Craig and Mara, lovers in The Girl With the Dragon Tattoo, is pretty wide. she was 29.
Emily Blunt and Tom Cruise: 20 Years
Blunt and Cruise co-star in this week's Edge of Tomorrow — Blunt is 31, while her love interest Cruise is 51.
Keira Knightley and Steve Carell: 22 Years
In Seeking a Friend For the End of the World, the relationship of Knightley and Carell's characters turns romantic, despite their age difference (at the time, he was 49, and she was 27).
Johnny Depp and Amber Heard: 23 Years
When Depp and Heard played love interests in 2011's The Rum Diary, he was 48, and she was 25. Obviously, the age difference didn't bother them - they're engaged in real life.
Harrison Ford and Anne Heche: 26 Years
Sure, the man who played Indiana Jones still looks great for his age, but when he co-starred with Anne Heche in 1998's Six Days Seven Nights, he was 55, and she was 29.
Colin Firth and Emma Stone: 28 Years
They're both ridiculously cute and both charming in the Magic in the Moonlight trailer, but in real life, Firth is 53, while Stone is 25. Yep, old enough to be her father.
Emma Stone and Sean Penn: 28 Years
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Now 53, Penn played the gangster boyfriend to young Stone, who's 25, in 2013's Gangster Squad. That's just three years older than Penn's oldest daughter Dylan.