For many, the love affair is a heady mix of sun, sand and sea. For others, it's the laid back lifestyle, ease of getting around, or the arts, culture, cafes and bars.
As the region celebrates its anniversary, the Nelson Mail sought your views on why you love living here.
There was no shortage of responses, reflecting the passion for our corner of the world.
More than 150 people from the Mail's readers panel responded to a survey and others posted to the Mail's Facebook page to count their blessings.
Some were succinct: "The weather!" Others were more lyrical: "I love the way the sky and the hills are mixed together so that wherever you look you always see a view of both. There is always a feast for the eyes," said reader Anna Heinz.
The most cited reasons were the region's weather and its great outdoors - the ability to explore its plentiful beaches, rivers, mountains, bush, parks and reserves.
But there was also a lot of love for the relaxed, warm and friendly inhabitants.
"Most of all is the warmth, openness and ease of connecting with caring others," said one reader.
"Coming from Auckland we have been overwhelmed by the friendliness of Nelson people," said another.
Others enthused about the arts and culture, cafes, bars and recreation facilities such as the newly opened Great Taste cycle trail.
Another common theme was the "right" size of Nelson and Richmond - big enough to have everything you need; small enough to have no trouble getting around.
"Parking outside the shop I want to go to," one said.
Asked what they would like to change about living here, the responses included cheaper airfares to and from Nelson, better wages, greater public transport and better local government.
Almost a third of those surveyed planned day trips within the region for their long weekend, with the top spots being Rabbit Island, Kaiteriteri and Golden Bay.
There was a wide variety of suggestions for what visitors to the region should see, from walking and biking trails, wineries and markets, to the WOW museum, Founders Heritage Park , Suter art gallery and trapping at the Brook Waimarama sanctuary.
One reader had a simple formula: "Swim, eat, drink, relax."