Argentina have made four changes, three in the backs, to face Ireland in Dublin in the third and final test of their European tour on Saturday.
Juan Martin Hernandez returns at fullback having missed last weekend's 39-22 loss to France in Lille due to leg muscle fatigue, replacing Lucas Gonzalez Amorosino.
Santiago Fernandez, a regular during the southern hemisphere's Rugby Championship, has joined the squad after missing the first two matches including the opening 26-12 win over Wales.
Fernandez takes his customary place at inside centre with Marcelo Bosch moving to number 13 and Gonzalo Tiesi stepping down to the bench.
Gonzalo Camacho, one of Argentina's try scorers against Wales, returns to the right wing in place of Horacio Agulla who has left the squad after suffering concussion against France.
In the pack, Maximiliano Bustos will make his debut at prop in place of Juan Figallo, who has been released back to his club Montpellier but would have missed the match anyway after being suspended for three weeks for head-butting.
Ireland rewarded Craig Gilroy for scoring a hat trick of tries in last weekend's thrashing by its second-string team of Fiji by putting him in their starting lineup.
Gilroy replaced Andrew Trimble in the only change to the side that started the 16-12 loss to South Africa on November 10. The 53-0 win over Fiji was classed as a non-cap international, meaning the 21-year-old Gilroy will be making his test debut.
Ireland is still without key players Brian O'Driscoll, Paul O'Connell, Rory Best, Stephen Ferris, Sean O'Brien and Rob Kearney.
The result of the match will carry major significance with the losers dropping into the third tier of seeds for the pool draw for the 2015 World Cup, which is made December 3.
The Irish have lost their past five tests, their worst run for 14 years, placing coach Declan Kidney under pressure.
Argentina: Juan Martin Hernandez, Gonzalo Camacho, Marcelo Bosch, Santiago Fernandez, Juan Imhoff, Nicolas Sanchez, Martin Landajo, Leonardo Senatore, Juan Manuel Leguizamon, Juan Martin Fernandez Lobbe (captain), Julio Farias Cabello, Manuel Carizza, Maximiliano Bustos, Eusebio Guinazu, Marcos Ayerza. Reserves: Agustin Creevy, Nahuel Lobo, Francisco Gomez Kodela, Tomas Vallejos, Tomas Leonardi, Nicolas Vergallo, Gonzalo Tiesi, Manuel Montero.
Ireland: Simon Zebo, Tommy Bowe, Keith Earls, Gordon D'Arcy, Craig Gilroy, Jonathan Sexton, Conor Murray; Jamie Heaslip (captain), Chris Henry, Peter O'Mahony, Mike McCarthy, Donnacha Ryan, Mike Ross, Richardt Strauss, Cian Healy. Reserves: Sean Cronin, David Kilcoyne, Michael Bent, Donncha O'Callaghan, Iain Henderson, Eoin Reddan, Ronan O'Gara, Fergus McFadden.
- Reuters and AP