Industry analysts and safety experts say they can find no common themes. Nor do they think the events indicate that flying is suddenly becoming less safe.
Fewer than one in two million flights last year ended in an accident in which the plane was damaged beyond repair, according to the International Air Transport Association.
That includes accidents involving cargo and charter airlines as well as scheduled passenger flights.
"One of the things that makes me feel better when we look at these events is that if they all were the same type event or same root cause then you would say there's a systemic problem here, but each event is unique in its own way," said Jon Beatty, president and CEO of the Flight Safety Foundation, an airline industry-supported nonprofit in the US that promotes global aviation safety.
But Beatty said he also finds the disaster cluster "a cold reminder" that airline accidents are likely to increase because the industry is growing, especially in developing countries. The more flights there are, the more potential for accidents, he said.
The misfortunes began July 18 when Malaysia Airlines flight MH17 was shot down over eastern Ukraine with 298 people on board. It's still not clear who fired the missile that destroyed the plane, but Ukrainian officials have blamed pro-Russian rebels.
The mysterious disappearance in March of Malaysia Airlines flight MH370 with 239 people on board, combined with the destruction of MH17, added up to more than twice the total global airline fatalities in all of last year, which was the industry's safest year on record.
Ascend, a global aviation industry consulting firm based in London, counted 163 fatalities in 2013 involving airliners with 14 seats or more.
On Wednesday ngiht, a TransAsia Airways plane crashed in Taiwan in stormy weather trailing a typhoon, killing 48 passengers, injuring 10 others and crew and injuring five people on the ground.
On Thursday, an Air Algerie flight with 116 passengers and crew disappeared in a rainstorm over Mali en route from Burkina Faso to Algeria's capital. The plane was operated for the airline by Swiftair, a Spanish carrier.
Together, the disasters have the potential to push airline fatalities this year to over 700 - the most since 2010. And 2014 is still barely half over.
Aviation industry analyst Robert Mann said he didn't expect the recent events to deter travellers from flying.
"They're all tragic, but the global air travel consumer has a very short memory, and it's highly localised to their home markets where they fly," he said.
Airline passengers interviewed by The Associated Press said they weren't overly concerned about their safety.
"It could be happening every day or never again," said Bram Holshoff, a Netherlands traveler at Berlin's Tegel Airport. "It's a bit much that it happened three times this week, but for me nothing will change."
Lam Nguyen, 52, of Tahiti, who was headed to Los Angeles from Paris' Charles de Gaulle airport, said he considers flying "a very safe mode of transportation."
"And if it has to happen, it will happen....It doesn't prevent me from taking planes," he said.
The shootdown of MH17 has raised questions about whether airlines, and the aviation authorities in their home countries, are adjusting flight routes quickly enough when unrest in troubled parts of the world threatens the safety of planes.
But aviation safety consultant John Cox, a former airline pilot and accident investigator, said he sees no connection between that event and the other disasters.
"I don't know how you could respond to anything when there is not a commonality of events," he said. "We don't have a full understanding of the Taiwan accident, and certainly not on the" Air Algerie plane.
Cox attributed the US Federal Aviation Administration's decision on Tuesday to prohibit flights to Ben Gurion International Airport in Tel Aviv to "hypersensitivity" to the possibility of another shootdown.
The FAA issued the order after a Hamas rocket exploded about 1.6 kilometres from the airport. The prohibition was lifted 36 hours later.
Aviation is "fundamentally safe and getting safer, but can it can always fall prey to the mistakes or ill will of man," said former FAA chief counsel Kenneth Quinn.
"We sometimes forget the magic of flight, or the fragility of life, but this week has brought home the need to appreciate this more and protect both better."