Swine flu resisting Tamiflu

Last updated 07:34 30/06/2009
Tamiflu
ANTIVIRAL DRUG: The first case of swine flu resisting the Tamiflu drug has been found in Denmark.

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The first case of swine flu showing resistance to Tamiflu, the main antiviral flu drug, has been discovered in Denmark.

It was expected that the strain would at some point show resistance to Tamiflu, Denmark's State Serum Institute said.

The patient was now well and no further infection with the resistant virus had been detected.

"It does not constitute a risk to public health and does not cause changes to the recommendations for the use of oseltamivir (Tamiflu)," the institute said in a statement.

The World Health Organisation declared an influenza pandemic earlier this month and advised governments to prepare for a long-term battle against an unstoppable new flu virus.

The WHO had no immediate comment on the case of Tamiflu resistance.

The United Nations agency has raised its pandemic flu alert to its highest alert level of six, indicating the first influenza pandemic since 1968 is underway.

Flu viruses mutate regularly and can develop resistance to drugs at any time. The seasonal strain of H1N1 is a distant cousin of the swine flu and was widely resistant to Tamiflu this year.

Common seasonal flu can resist Tamiflu and David Reddy, Roche's pandemic taskforce leader, said a case of resistance in H1N1 - also know as swine flu - was not unexpected.

Roche had been working on strategies to counter such a development, Reddy said.

NO THREAT TO PUBLIC HEALTH

The WHO has said Tamiflu was working against strains of the new H1N1 flu but some analysts have expressed concern it might be less effective than Relenza, GlaxoSmithKline's inhaled drug, since there have been widespread reports of resistance by seasonal H1N1 flu.

Roche stock closed up 1.4 percent at 149 Swiss francs, outperforming a 0.7 percent firmer DJ Stoxx European drugs index.

Surveillance for antiviral resistance in the new strain is continuing, though the isolated case in Denmark does not pose a threat to public health or reason to change recommendations for use of Tamiflu, said David Daigle, a spokesman for the US Centres for Disease Control and Preventiom.

"It is well known and expected that influenza virus can mutate spontaneously.

"The resistance has not changed the capability of the virus to transmit or cause disease, and the assessment is still that this is a relatively mild influenza," Daigle said.

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- Reuters

 

9 comments
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Jesse   #9   02:31 pm Jul 01 2009

I realise tamiflu is just an antiviral drug but Im sure they will release a vaccine for H1N1 very soon, as far as polio and smallpox several studies have proven that these infectious diseases were almost completely gone before the vaccines were introduced. From 1850 to 1940, polio diseases had declined by 90% and were at an all time low, just when vaccines were being introduced, another example of a vaccine being released during a steep natural decline was the meningococcal B vaccine in 2004.

Lys   #8   04:23 pm Jun 30 2009

Agreed that Swine Flu has been blown greatly out of proportion and Tamiflu is most likely unnecessary for recovery if you have no prior health/immune problems, as it is just a flu.

But Jesse, firstly Tamiflu is not a vaccine, it is an antiviral, there is quite a difference. And secondly, yes there are plenty of things manufactured for the sake of profit, but don't be so quick to right off all vaccines. Polio and Smallpox for example killed (and paralyzed in the former case) hundreds of thousands of people every year before they were eradicated by vaccination. Sometimes even "healthy" people can benefit from "unnaturally manufactured vaccines".

Jesse   #7   02:13 pm Jun 30 2009

A healthy person is capable of recovering as long as we refrain from injecting unnaturally manufactured vaccines into the bodies of ourselves, children, and livestock. All you need to ask yourself to determine if this is evil in nature: Why do we need a vaccination against something less lethal than the annual flu?

Create a fear, manufacture, sell the cure…simple economics

mantee   #6   02:12 pm Jun 30 2009

#1 Justin, DEAR LORD! how big would you say these 'Superbugs' are? Like Megatron size or more like your average dog? still, this is terrifying and i am living in fear now.

Pow   #5   01:19 pm Jun 30 2009

A virus will always mutate, that's what they do. Our immune systems effectively mutate too to combat such viruses.

Don't take drugs and medicine for every little cough you get, stay warm, wash your hands and let your immune system develop and become strong.

The real problem is people being so susceptible to fear mongering in the media. Swine Flu is just a reiteration of SARS or bird flu or whatever.

Swine flu is just a Government funded recession escape for drug companies. What a load of crap.

BX   #4   12:49 pm Jun 30 2009

Stephen #2 - Id like to believe that you are a ground breaking scientist who has dedicated hours of research to the human immune system and the effect drugs have on bacteria, viruses and the human body. That you have used all available resources to come to your conclusion. But.... somehow I don't think so.

Tamilfu has 'dodgy' written all over it anyway, if people had any common sense they wouldn't be taking it (theres plentry of material available to prove this). Besides its just an anti-viral drug anyway its not a 'cure'

Random   #3   12:13 pm Jun 30 2009

Thankfully humans aren't entirely stupid and are starting to show some resistance to the paranoia surrounding swine flu.

Stephen   #2   10:19 am Jun 30 2009

#1 Justice. Get a life. Influenza would mutate to avoid our bodies natural defences without any "meddling".

Think before you speak. Amateur.

justice   #1   10:00 am Jun 30 2009

live in fear people!, not of H1N1 but of huge pharma companies that help create these superbugs in the first place by their constant meddling with nature!

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