A Syrian government airstrike has hit a crowded vegetable market in a rebel-held neighbourhood of the northern city of Aleppo, shattering cars and storefronts and killing at least 21 people, activists said.
For nearly two weeks, President Bashar Assad's warplanes and helicopters have pounded opposition-controlled areas of the divided city. Activists say the aerial assault has killed more than 400 people since it began December 15.
The campaign comes in the run-up to an international peace conference scheduled to start January 22 in Switzerland to try to find a political solution to Syria's civil war. Some observers say the Aleppo assault fits into Assad's apparent strategy of trying to expose the opposition's weakness to strengthen his own hand ahead of the negotiations.
Saturday's airstrike (local time) slammed into a marketplace in the Tariq al-Bab neighbourhood, the Aleppo Media Centre activist group and the Britain-based Syrian Observatory for Human Rights said.
The Observatory, which relies on a network of activists on the ground, said 25 people, including four children, were killed and dozens were wounded in the strike. The Aleppo Media Centre published a list of 21 names of people it said were killed in the air raid.
The discrepancy could not be immediate reconciled, but differing death tolls are common in the chaotic aftermath of such attacks.
An activist with the Aleppo Media Centre, Hassoun Abu Faisal, said the airstrike took place about 10am local time when the market was packed with shoppers.
"Cars were damaged, debris and rubble are everywhere," he said via Skype. "Many of the wounded have lost limbs."
One amateur video posted online showed scenes of carnage: a body, its legs twister under it, lying in a pool of blood in front of a smashed car; the body of another man ripped in half in the middle of the street; men rushing a limp body past shattered storefronts.
In another video, blankets cover at least three bodies placed on a sidewalk. Muddy black shoes poke out from under one of the blankets.
The videos appeared genuine and corresponded to other AP reporting of the events depicted.
Both Abu Faisal and the Observatory reported airstrikes in other opposition-held areas of Aleppo, including Myassar, although there was no immediate word on casualties.
Aleppo, Syria's largest city, has been a major front in the country's civil war since rebels launched an offensive there in mid-2012. The city has been heavily damaged since then in fighting that has left it divided into rebel- and government-controlled areas.
Another critical battleground is around the capital, Damascus. Assad's forces have a tight grip on the heart of the city, but many of the suburbs have been opposition strongholds since the early days of the uprising.
In a gruelling campaign that has lasted months, government forces have managed to capture some of the rebel-held towns and villages ringing Damascus, while others have held out despite daily shelling and months-long sieges.
One such town is Moadamiyeh, which activists say has been strangled by a government siege for nearly a year. Assad's troops have set up checkpoints around the community west of Damascus, and have barred entry to food, clean water and fuel in a bid to pressure residents to expel rebels from the town.
The blockade has had a devastating effect on those stuck inside. For months, activists in Moadamiyeh have warned that malnutrition is rife among the town's estimated 8000 civilians. They say at least two women and four children died of hunger-related illnesses by September.
This week, residents reached a deal with the army that would see the town receive food in exchange for raising the government flag over Moadamiyeh. The agreement also demanded rebels hand over their heavy weapons and that only registered residents may remain in the town.
Locals hoisted the flag above Moadamiyeh on Thursday. Late Saturday afternoon, three small pickup trucks entered with bread, rice and canned food, said Moadamiyeh-based activist Qusai Zakarya.
"It's very, very small shipment. We have over 8000 civilians. They have brought in around three tons of food," he said. "This amount of food won't be enough for 1000 civilians for one day."
He said residents want the government to allow large, continuous shipments of food such as flour, rice and canned goods, so the town can store the items in case the supply line is cut. He alleged the government agreed to the deal in order to improve its image ahead of peace talks expected next month in Switzerland, but said it would only send small shipments so that it can maintain its hold over Moadamiyeh.
He also said faith in the government to carry out its end of the deal was running low after the army attacked the town on Friday, sparking a six-hour battle with rebels that ended with Assad's forces pulling back.
"We know that we cannot trust the regime to have continuous food entering the town. They might change their minds at any second," Zakarya said. "They are just trying to make these sorts of arrangements before going to Geneva to tell the world, 'look, I have solved this problem'."
There was no immediate comment from Syrian officials.
Rights groups have accused the government of using starvation as a weapon of war, and the UN Security Council issued an appeal in October for immediate access to all areas of Syria to deliver desperately needed humanitarian aid.
Also Saturday, the UN-backed international mission to rid Syria of its chemical weapons confirmed that it is unlikely to meet a December 31 deadline to transport the most critical chemical material out of the country.
A statement by the joint mission of the Organization for the Prohibition of Chemical Weapons and the UN said that external factors, primarily security concerns, were responsible for the delay.
At the Vatican, meanwhile, a Syrian delegation delivered a message from Assad to Pope Francis during a meeting with the Holy See's No 2 Secretary of State, Monsignor Pietro Parolin, the Vatican said. It did not disclose the contents of the Syrian leader's message, nor the pope's reaction.
The pontiff has called for an end to the hostilities in Syria, most recently on Christmas.